Disclaimers, compliance & terms of use

Educational purposes only. This platform does not provide medical advice, diagnosis, or treatment. Always consult a qualified gastroenterologist before starting any supplement or changing prescription regimens.

Nothing on this site constitutes a diagnosis, a treatment plan, a prescription, or a professional opinion about your individual circumstances. No doctor–patient relationship is created by reading this site, contacting it, or using any material on it. Crohn’s disease varies enormously between individuals in location, behaviour, severity and treatment history, and information written for a general audience cannot account for that.

If you are experiencing severe abdominal pain, persistent vomiting, high fever, significant rectal bleeding, or signs of bowel obstruction, seek emergency medical care immediately rather than consulting a web page.

Discontinuing or reducing maintenance therapy for Crohn’s disease — including biologics such as Humira, Remicade, Stelara, Skyrizi and Entyvio, immunomodulators such as azathioprine, or corticosteroids such as prednisone — is associated with disease flare, stricture formation, fistulising complications and surgery.

Corticosteroids in particular must never be stopped abruptly: doing so can cause adrenal insufficiency, which is potentially life-threatening. Any change to a prescription regimen must be planned and supervised by the clinician who prescribed it.

Comparative content on this site exists to explain how mechanisms and evidence differ. It is not a substitution guide, and no comparison on this site should be read as a suggestion that a supplement can take the place of a prescribed medication.

Statements on this site have not been evaluated by the Food and Drug Administration. No dietary supplement, herb, peptide or nutrient described here is intended to diagnose, treat, cure or prevent any disease.

Several compounds described on this site — including BPC-157 — are not approved as drugs in any jurisdiction and are not legally marketed for human consumption. Their inclusion is a description of the published research record, not an endorsement of their use or an assertion that they are legal to purchase or take where you live.

Dietary supplements in the United States are regulated as food rather than as drugs. They are not required to demonstrate efficacy before sale, and manufacturing quality, purity and actual content vary substantially between products.

This site contains affiliate links and may display advertising. We may earn a commission when you purchase through links on our pages, at no extra cost to you. Editorial content is written independently of any commercial relationship, and no brand pays to be included. These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

Links in our “Recommended sourcing” sections and retailer buttons are affiliate links. If you buy through them, we may earn a commission at no extra cost to you. We may also display third-party advertising. See our full affiliate disclosure at /affiliate-disclosure.

No company pays to be included on this site or to influence how research is described. Commercial relationships do not determine which compounds we cover.

Research summaries reference third-party published studies, and every study we describe links to its source. We encourage readers to consult the primary literature directly. Where a summary on this site conflicts with the source paper, the source paper governs.

Summaries are necessarily compressed and may omit detail about patient selection, endpoint definitions, statistical methods, conflicts of interest or subsequent criticism of a study. Research evolves; a cited finding may be superseded after publication here.

Prevalence figures, dose ranges and protocols are reported as they appear in the cited literature. They describe what researchers measured or administered under supervision, and are not instructions.

Herbal and supplement products interact with prescription medication. Several compounds described on this site inhibit cytochrome P450 enzymes or P-glycoprotein and can raise blood levels of immunosuppressants, which is a clinically significant risk in an IBD population.

Supplements may also affect bleeding risk, liver function, blood glucose and seizure threshold. Anyone taking thiopurines, methotrexate, biologics, anticoagulants or anticonvulsants, anyone who is pregnant or breastfeeding, and anyone approaching surgery should review any supplement with their clinical team before starting it.

This site is provided on an "as is" and "as available" basis without warranties of any kind, express or implied, including warranties of accuracy, completeness, fitness for a particular purpose or non-infringement.

To the fullest extent permitted by law, the operators of this site accept no liability for any loss, injury or damage arising from reliance on its content or on any third-party site linked from it. Outbound links are provided for verification of sources and do not imply endorsement of the linked organisation.

Use of this site constitutes acceptance of these terms. If you do not accept them, please do not use the site.

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